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Details for receptor: sst4

EndoNet ID: ENR00921

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  • somatostatin receptor 4
  • SSTR4
  • sst(4)
  • sst4

General information

  • SSTR3 and SSTR4 were relatively poorly expressed in beta cells. [1]
  • Belongs to the seven transmembrane domain receptor family. [2]

Links to other resources

UniProt P31391
Ensembl ENST00000255008

Binding hormones

  • somatostatin
    • There are five distinct subtypes of SSTR that bind the two natural ligands, SST-14 and SST-28. [3]
  • somatostatin-28
  • somatostatin-14
  • cortistatin
    • CST-17 and its rodent homologue CST-14 both bind nonselectively and with nanomolar affinities to all five somatostatin receptor subtypes in vitro. [4]

Anatomical structures with this receptor

  • brain

  • hippocampus

  • stomach

  • lung

  • placenta

  • beta_cell_of_islet_of_Langerhans


    • negative insulin