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Details for receptor: adiponectin receptor 1

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EndoNet ID: ENR00953

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Synonyms

  • adiponectin receptor 1
  • ADIPOR1
  • progestin and adipoQ receptor family member I
  • AdipoR1
  • adiponectin receptor protein 1

General information

  • AdipoR1 is abundantly expressed in skeletal muscle. [1]
  • AdipoR1 and AdipoR2 serve as receptors for globular and full-length adiponectin and mediate increased AMP-activated protein kinase, peroxisome proliferator-activated receptor-alpha ligand activities, and glucose uptake and fatty-acid oxidation by adiponectin. [2]
  • The two adiponectin receptors are predicted to contain seven transmembrane domains, but to be structurally and functionally distinct from G-protein-coupled receptors. [1]

Links to other resources

UniProt Q96A54
Ensembl ENST00000436244

Subunit information

adiponectin receptor protein 1

Sequence 
MSSHKGSVV AQGNGAPAS NREADTVEL 
AELGPLLEE KGKRVIANP PKAEEEQTC 
PVPQEEEEE VRVLTLPLQ AHHAMEKME 
EFVYKVWEG RWRVIPYDV LPDWLKDND 
YLLHGHRPP MPSFRACFK SIFRIHTET 
GNIWTHLLG FVLFLFLGI LTMLRPNMY 
FMAPLQEKV VFGMFFLGA VLCLSFSWL 
FHTVYCHSE KVSRTFSKL DYSGIALLI 
MGSFVPWLY YSFYCSPQP RLIYLSIVC 
VLGISAIIV AQWDRFATP KHRQTRAGV 
FLGLGLSGV VPTMHFTIA EGFVKATTV 
GQMGWFFLM AVMYITGAG LYAARIPER 
FFPGKFDIW FQSHQIFHV LVVAAAFVH 
FYGVSNLQE FRYGLEGGC TDDTLL

Binding hormones

  • adiponectin

Anatomical structures with this receptor

    Reference