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Details for receptor: adiponectin receptor 2

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EndoNet ID: ENR00954

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Synonyms

  • adiponectin receptor 2
  • ADIPOR2
  • AdipoR2
  • progestin and adipoQ receptor family member II
  • adiponectin receptor protein 2

General information

  • AdipoR1 and AdipoR2 serve as receptors for globular and full-length adiponectin and mediate increased AMP-activated protein kinase, peroxisome proliferator-activated receptor-alpha ligand activities, and glucose uptake and fatty-acid oxidation by adiponectin. [1]
  • The two adiponectin receptors are predicted to contain seven transmembrane domains, but to be structurally and functionally distinct from G-protein-coupled receptors. [2]
  • AdipoR2 is predominantly expressed in the liver. [2]

Links to other resources

UniProt Q86V24
Ensembl ENST00000357103

Subunit information

adiponectin receptor protein 2

Sequence 
MNEPTENRL GCSRTPEPD IRLRKGHQL 
DGTRRGDND SHQGDLEPI LEASVLSSH 
HKKSSEEHE YSDEAPQED EGFMGMSPL 
LQAHHAMEK MEEFVCKVW EGRWRVIPH 
DVLPDWLKD NDFLLHGHR PPMPSFRAC 
FKSIFRIHT ETGNIWTHL LGCVFFLCL 
GIFYMFRPN ISFVAPLQE KVVFGLFFL 
GAILCLSFS WLFHTVYCH SEGVSRLFS 
KLDYSGIAL LIMGSFVPW LYYSFYCNP 
QPCFIYLIV ICVLGIAAI IVSQWDMFA 
TPQYRGVRA GVFLGLGLS GIIPTLHYV 
ISEGFLKAA TIGQIGWLM LMASLYITG 
AALYAARIP ERFFPGKCD IWFHSHQLF 
HIFVVAGAF VHFHGVSNL QEFRFMIGG 
GCSEEDAL

Binding hormones

  • adiponectin

Anatomical structures with this receptor

    Reference