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Details for receptor: adrenomedullin receptor

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EndoNet ID: ENR00956

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
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Synonyms

  • ADMR
  • adrenomedullin receptor

General information

  • ADM receptors are formed by heterodimerization of the CRLR and a RAMP2 or RAMP3 molecule. [1]
  • The AM receptor, a complex formed by calcitonin receptor-like receptor (CRLR) and receptor activity-modifying proteins (RAMPs), and the recently discovered AM-binding protein, complement factor H (fH), are expressed in the insulin-producing beta-cells. [2]

Links to other resources

UniProt O15218
Ensembl ENST00000300098

Subunit information

Sequence 
MSVKPSWGP GPSEGVTAV PTSDLGEIH 
NWTELLDLF NHTLSECHV ELSQSTKRV 
VLFALYLAM FVVGLVENL LVICVNWRG 
SGRAGLMNL YILNMAIAD LGIVLSLPV 
WMLEVTLDY TWLWGSFSC RFTHYFYFV 
NMYSSIFFL VCLSVDRYV TLTSASPSW 
QRYQHRVRR AMCAGIWVL SAIIPLPEV 
VHIQLVEGP EPMCLFMAP FETYSTWAL 
AVALSTTIL GFLLPFPLI TVFNVLTAC 
RLRQPGQPK SRRHCLLLC AYVAVFVMC 
WLPYHVTLL LLTLHGTHI SLHCHLVHL 
LYFFYDVID CFSMLHCVI NPILYNFLS 
PHFRGRLLN AVVHYLPKD QTKAGTCAS 
SSSCSTQHS IIITKGDSQ PAAAAPHPE 
PSLSFQAHH LLPNTSPIS PTQPLTPS

Binding hormones

  • ADM

Anatomical structures with this receptor

  • beta_cell_of_islet_of_Langerhans

    Influences

    • negative insulin
Reference