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Details for receptor: IL-17R

EndoNet ID: ENR01006

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Synonyms

  • IL-17R
  • interleukin-17 receptor

General information

Links to other resources

UniProt Q96F46
Ensembl ENST00000425985

Subunit information

Sequence
LRLLDHRAL VCSQPGLNC TVKNSTCLD 
DSWIHPRNL TPSSPKDLQ IQLHFAHTQ 
QGDLFPVAH IEWTLQTDA SILYLEGAE 
LSVLQLNTN ERLCVRFEF LSKLRHHHR 
RWRFTFSHF VVDPDQEYE VTVHHLPKP 
IPDGDPNHQ SKNFLVPDC EHARMKVTT 
PCMSSGSLW DPNITVETL EAHQLRVSF 
TLWNESTHY QILLTSFPH MENHSCFEH 
MHHIPAPRP EEFHQRSNV TLTLRNLKG 
CCRHQVQIQ PFFSSCLND CLRHSATVS 
CPEMPDTPE PIPDYMPLW VYWFITGIS 
ILLVGSVIL LIVCMTWRL AGPGSEKYS 
DDTKYTDGL PVADLIPPP LKPRKVWII 
YSADHPLYV DVVLKFAQF LLTACGTEV 
ALDLLEEQA ISEAGVMTW VGRQKQEMV 
ESNSKIIVL CSRGTRAKW QALLGRGAP 
VRLRCDHGK PVGDLFTAA MNMILPDFK 
RPACFGTYV VCYFSEVSC DGDVPDLFG 
AAPRYPLMD RFEEVYFRI QDLEMFQPG 
RMHRVGELS GDNYLRSPG GRQLRAALD 
RFRDWQVHC PDWFECENL YSADDQDAP 
SLDEEVFEE PLLPPGTGI VKRAPLVRE 
PGSQACLAI DPLVGEEGG AAVAKLEPH 
LQPRGQPAP QPLHTLVLA AEEGALVAA 
VEPGPLADG AAVRLALAG EGEACPLLG 
SPGAGRNSV LFLPVDPED SPLGSSTPM 
ASPDLLPED VREHLEGLM LSLFEQSLS 
CQAQGGCSR PAMVLTDPH TPYEEEQRQ 
SVQSDQGYI SRSSPQPPE GLTEMEEEE 
EEEQDPGKP ALPLSPEDL ESLRSLQRQ 
LLFRQLQKN SGWDTMGSE SEGPSA

Binding hormones

  • IL-17A
  • IL-17B
  • IL-17F
    • IL17RA is a receptor for IL17F. [1]

Anatomical structures with this receptor

  • bronchi

    Influences

    • positive IL-8
      • Compared to baseline (inherent) release, the peak response of interleukin-17-induced release of interleukin-8 was 225% (+/- 13%). [2]
    • positive GROalpha
      • Compared to baseline (inherent) release, the peak response of interleukin-17-induced release of GRO-alpha was 259% (+/-12%). [2]
Reference