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Details for receptor: IL -3R

EndoNet ID: ENR01011

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Synonyms

  • IL3R
  • interleukin 3 receptor
  • IL -3R

General information

  • Heterodimer of IL-3Ralpha and human CSF2RB. The beta chain is common to the IL3, IL5 and GM-CSF receptors.

Links to other resources

Subunit information

interleukin-3 receptor alpha chain (1 times)

Sequence
TKEDPNPPI TNLRMKAKA QQLTWDLNR 
NVTDIECVK DADYSMPAV NNSYCQFGA 
ISLCEVTNY TVRVANPPF STWILFPEN 
SGKPWAGAE NLTCWIHDV DFLSCSWAV 
GPGAPADVQ YDLYLNVAN RRQQYECLH 
YKTDAQGTR IGCRFDDIS RLSSGSQSS 
HILVRGRSA AFGIPCTDK FVVFSQIEI 
LTPPNMTAK CNKTHSFMH WKMRSHFNR 
KFRYELQIQ KRMQPVITE QVRDRTSFQ 
LLNPGTYTV QIRARERVY EFLSAWSTP 
QRFECDQEE GANTRAWRT SLLIALGTL 
LALVCVFVI CRRYLVMQR LFPRIPHMK 
DPIGDSFQN DKLVVWEAG KAGLEECLV 
TEVQVVQKT
UniProt P26951

cytokine receptor common beta chain (1 times)

Sequence
WERSLAGAE ETIPLQTLR CYNDYTSHI 
TCRWADTQD AQRLVNVTL IRRVNEDLL 
EPVSCDLSD DMPWSACPH PRCVPRRCV 
IPCQSFVVT DVDYFSFQP DRPLGTRLT 
VTLTQHVQP PEPRDLQIS TDQDHFLLT 
WSVALGSPQ SHWLSPGDL EFEVVYKRL 
QDSWEDAAI LLSNTSQAT LGPEHLMPS 
STYVARVRT RLAPGSRLS GRPSKWSPE 
VCWDSQPGD EAQPQNLEC FFDGAAVLS 
CSWEVRKEV ASSVSFGLF YKPSPDAGE 
EECSPVLRE GLGSLHTRH HCQIPVPDP 
ATHGQYIVS VQPRRAEKH IKSSVNIQM 
APPSLNVTK DGDSYSLRW ETMKMRYEH 
IDHTFEIQY RKDTATWKD SKTETLQNA 
HSMALPALE PSTRYWARV RVRTSRTGY 
NGIWSEWSE ARSWDTESV LPMWVLALI 
VIFLTIAVL LALRFCGIY GYRLRRKWE 
EKIPNPSKS HLFQNGSAE LWPPGSMSA 
FTSGSPPHQ GPWGSRFPE LEGVFPVGF 
GDSEVSPLT IEDPKHVCD PPSGPDTTP 
AASDLPTEQ PPSPQPGPP AASHTPEKQ 
ASSFDFNGP YLGPPHSRS LPDILGQPE 
PPQEGGSQK SPPPGSLEY LCLPAGGQV 
QLVPLAQAM GPGQAVEVE RRPSQGAAG 
SPSLESGGG PAPPALGPR VGGQDQKDS 
PVAIPMSSG DTEDPGVAS GYVSSADLV 
FTPNSGASS VSLVPSLGL PSDQTPSLC 
PGLASGPPG APGPVKSGF EGYVELPPI 
EGRSPRSPR NNPVPPEAK SPVLNPGER 
PADVSPTSP QPEGLLVLQ QVGDYCFLP 
GLGPGPLSL RSKPSSPGP GPEIKNLDQ 
AFQVKKPPG QAVPQVPVI QLFKALKQQ 
DYLSLPPWE VNKPGEVC
UniProt P32927

Binding hormones

  • IL-3

Anatomical structures with this receptor

  • hematopoietic_stem_cell

Reference