Details for receptor: vitronectin receptor

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EndoNet ID: ENR01013

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Synonyms

CD51 antigen
ITGAV
VNRA
integrin alpha V
integrin alpha-V
vitronectin receptor alpha subunit
vitronectin receptor
Vitronectin receptor subunit alpha
Vitronectin receptor subunit alpha

General information

The membrane receptors integrins alpha V recognize the sequence R-G-D in a wide array of ligands, and are therefor receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and von Willebrand factor.

Links to other resources

UniProt	P06756
Ensembl	ENST00000433736

Subunit information

Integrin alpha-V heavy chain

Sequence

FNLDVDSPA EYSGPEGSY FGFAVDFFV 
PSASSRMFL LVGAPKANT TQPGIVEGG 
QVLKCDWSS TRRCQPIEF DATGNRDYA 
KDDPLEFKS HQWFGASVR SKQDKILAC 
APLYHWRTE MKQEREPVG TCFLQDGTK 
TVEYAPCRS QDIDADGQG FCQGGFSID 
FTKADRVLL GGPGSFYWQ GQLISDQVA 
EIVSKYDPN VYSIKYNNQ LATRTAQAI 
FDDSYLGYS VAVGDFNGD GIDDFVSGV 
PRAARTLGM VYIYDGKNM SSLYNFTGE 
QMAAYFGFS VAATDINGD DYADVFIGA 
PLFMDRGSD GKLQEVGQV SVSLQRASG 
DFQTTKLNG FEVFARFGS AIAPLGDLD 
QDGFNDIAI AAPYGGEDK KGIVYIFNG 
RSTGLNAVP SQILEGQWA ARSMPPSFG 
YSMKGATDI DKNGYPDLI VGAFGVDRA 
ILYRARPVI TVNAGLEVY PSILNQDNK 
TCSLPGTAL KVSCFNVRF CLKADGKGV 
LPRKLNFQV ELLLDKLKQ KGAIRRALF 
LYSRSPSHS KNMTISRGG LMQCEELIA 
YLRDESEFR DKLTPITIF MEYRLDYRT 
AADTTGLQP ILNQFTPAN ISRQAHILL 
DCGEDNVCK PKLEVSVDS DQKKIYIGD 
DNPLTLIVK AQNQGEGAY EAELIVSIP 
LQADFIGVV RNNEALARL SCAFKTENQ 
TRQVVCDLG NPMKAGTQL LAGLRFSVH 
QQSEMDTSV KFDLQIQSS NLFDKVSPV 
VSHKVDLAV LAAVEIRGV SSPDHIFLP 
IPNWEHKEN PETEEDVGP VVQHIYELR 
NNGPSSFSK AMLHLQWPY KYNNNTLLY 
ILHYDIDGP MNCTSDMEI NPLRIKISS 
LQTTEKNDT VAGQGERDH LITK

UniProt

P06756

Integrin alpha-V light chain

Sequence	DLALSEGDI HTLGCGVAQ CLKIVCQVG RLDRGKSAI LYVKSLLWT ETFMNKENQ NHSYSLKSS ASFNVIEFP YKNLPIEDI TNSTLVTTN VTWGIQPAP MPVPVWVII LAVLAGLLL LAVLVFVMY RMGFFKRVR PPQEEQERE QLQPHENGE GNSET
UniProt	P06756

Integrin alpha-V