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Details for receptor: frizzled 9

EndoNet ID: ENR01031

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Synonyms

  • frizzled 9
  • Fz9
  • frizzled-9
  • Fz-9
  • hFz9
  • FzE6
  • frizzled homolog 9 (Drosophila)
  • Fzd9

General information

  • Frizzleds are cell surface receptor for Wnts. [1]

Links to other resources

UniProt O00144
Ensembl ENST00000344575

Subunit information

Sequence
LEIGRFDPE RGRGAAPCQ AVEIPMCRG 
IGYNLTRMP NLLGHTSQG EAAAELAEF 
APLVQYGCH SHLRFFLCS LYAPMCTDQ 
VSTPIPACR PMCEQARLR CAPIMEQFN 
FGWPDSLDC ARLPTRNDP HALCMEAPE 
NATAGPAEP HKGLGMLPV APRPARPPG 
DLGPGAGGS GTCENPEKF QYVEKSRSC 
APRCGPGVE VFWSRRDKD FALVWMAVW 
SALCFFSTA FTVLTFLLE PHRFQYPER 
PIIFLSMCY NVYSLAFLI RAVAGAQSV 
ACDQEAGAL YVIQEGLEN TGCTLVFLL 
LYYFGMASS LWWVVLTLT WFLAAGKKW 
GHEAIEAHG SYFHMAAWG LPALKTIVI 
LTLRKVAGD ELTGLCYVA STDAAALTG 
FVLVPLSGY LVLGSSFLL TGFVALFHI 
RKIMKTGGT NTEKLEKLM VKIGVFSIL 
YTVPATCVI VCYVYERLN MDFWRLRAT 
EQPCAAAAG PGGRRDCSL PGGSVPTVA 
VFMLKIFMS LVVGITSGV WVWSSKTFQ 
TWQSLCYRK IAAGRARAK ACRAPGSYG 
RGTHCHYKA PTVVLHMTK TDPSLENPT 
HL

Binding hormones

  • Wnt-8
  • WNT7A
  • WNT9A
    • Co-immunoprecipitation assays showed that Wnt9a was selectively bound to Frz4, Fzd7, and Frz9. [2]

Anatomical structures with this receptor

  • brain

  • eye

  • kidney

  • skeleton_muscle

  • testis

Reference