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Details for receptor: QRFP-R

EndoNet ID: ENR01054

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Synonyms

  • QRFP-R
  • orexigenic neuropeptide QRFP receptor
  • G-protein coupled receptor 103
  • SP9155
  • AQ27
  • GPR103

General information

  • Expressed widely in the brain with high levels in the hypothalamus, trigeminal ganglia and vestibular neurons, moderate levels in the amygdala, cortex, pituitary, hippocampus, thalamus, caudate nucleus and medulla oblongata. In peripheral tissues, expressed at high levels in the retina,at moderate levels in the heart, kidney, testis and thyroid. [1]

Links to other resources

UniProt Q96P65
Ensembl ENST00000394427

Subunit information

Sequence
MQALNITPE QFSRLLRDH NLTREQFIA 
LYRLRPLVY TPELPGRAK LALVLTGVL 
IFALALFGN ALVFYVVTR SKAMRTVTN 
IFICSLALS DLLITFFCI PVTMLQNIS 
DNWLGGAFI CKMVPFVQS TAVVTEILT 
MTCIAVERH QGLVHPFKM KWQYTNRRA 
FTMLGVVWL VAVIVGSPM WHVQQLEIK 
YDFLYEKEH ICCLEEWTS PVHQKIYTT 
FILVILFLL PLMVMLILY SKIGYELWI 
KKRVGDGSV LRTIHGKEM SKIARKKKR 
AVIMMVTVV ALFAVCWAP FHVVHMMIE 
YSNFEKEYD DVTIKMIFA IVQIIGFSN 
SICNPIVYA FMNENFKKN VLSAVCYCI 
VNKTFSPAQ RHGNSGITM MRKKAKFSL 
RENPVEETK GEAFSDGNI EVKLCEQTE 
EKKKLKRHL ALFRSELAE NSPLDSGH

Binding hormones

  • QRFP

Anatomical structures with this receptor

  • cell_of_adrenal_gland_zona_glomerulosa

    Influences

    • positive aldosterone
      • Considered together with the expression of QRFP-R mRNA in the adrenal gland, these results indicate that QRFP acts directly on the zona glomerulosa to induce aldosterone secretion in rats. [2]
    • A high level of QFRP-R mRNA expression was detected in the zona glomerulosa of the adrenal gland. [2]
Reference