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Details for receptor: OPRL1

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EndoNet ID: ENR01060

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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Synonyms

  • OPRL1
  • orphanin FQ receptor
  • nociceptin receptor
  • kappa-type 3 opioid receptor
  • KOR-3
  • ORL1
  • OOR

General information

  • Nociceptin acts on ORL1 receptor on the keratinocytes to produce leukotriene B(4), which induces itch-associated responses. [1]

Links to other resources

UniProt P41146
Ensembl ENST00000450417

Subunit information

isoform 1

Sequence 
MEPLFPAPF WEVIYGSHL QGNLSLLSP 
NHSLLPPHL LLNASHGAF LPLGLKVTI 
VGLYLAVCV GGLLGNCLV MYVILRHTK 
MKTATNIYI FNLALADTL VLLTLPFQG 
TDILLGFWP FGNALCKTV IAIDYYNMF 
TSTFTLTAM SVDRYVAIC HPIRALDVR 
TSSKAQAVN VAIWALASV VGVPVAIMG 
SAQVEDEEI ECLVEIPTP QDYWGPVFA 
ICIFLFSFI VPVLVISVC YSLMIRRLR 
GVRLLSGSR EKDRNLRRI TRLVLVVVA 
VFVGCWTPV QVFVLAQGL GVQPSSETA 
VAILRFCTA LGYVNSCLN PILYAFLDE 
NFKACFRKF CCASALRRD VQVSDRVRS 
IAKDVALAC KTSETVPRP A
UniProt P41146-1

Binding hormones

  • nociceptin

Anatomical structures with this receptor

  • isocortex

  • hypothalamus

  • hippocampus

  • amygdaloid_body

  • substantia_nigra

  • spinal_cord

Reference