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Details for receptor: FGF-BP

EndoNet ID: ENR01084

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Synonyms

  • FGF-BP
  • fibroblast growth factor-binding protein
  • fibroblast growth factor-binding protein 1
  • FGF-binding protein 1
  • FGF-BP1
  • FGFBP-1
  • 17 kDa HBGF-binding protein
  • HBp17
  • FGFBP1
  • FGFBP
  • HBP17

General information

  • The expression of FGF-BP increases after injury to murine and human skin, in particular in keratinocytes. [1]
  • The fibroblast growth factor-binding protein (FGF-BP) binds and activates FGF-1 and FGF-2, thereby contributing to tumor angiogenesis. [1]
  • FGF-BP interacts with FGF-7, FGF-10, and with the recently identified FGF-22, and enhances the activity of low concentrations of ligand. [1]

Links to other resources

UniProt Q14512
Ensembl ENST00000382333

Subunit information

Fibroblast growth factor-binding protein 1.

Sequence
KKKVKNGLH SKVVSEQKD TLGNTQIKQ 
KSRPGNKGK FVTKDQANC RWAATEQEE 
GISLKVECT QLDHEFSCV FAGNPTSCL 
KLKDERVYW KQVARNLRS QKDICRYSK 
TAVKTRVCR KDFPESSLK LVSSTLFGN 
TKPRKEKTE MSPREHIKG KETTPSSLA 
VTQTMATKA PECVEDPDM ANQRKTALE 
FCGETWSSL CTFFLSIVQ DTSC
UniProt Q14512

Binding hormones

  • FGF-1 isoform 1
  • FGF-2
  • FGF-7
  • FGF-10
  • FGF-22

Anatomical structures with this receptor

  • hair_follicle

  • skin

Reference