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Details for receptor: integrin alpha-5/beta-1

EndoNet ID: ENR01105

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  • integrin alpha-5/beta-1
  • integrin alpha5/beta1
  • integrin alpha5beta1
  • integrin alpha5-beta1

General information

  • Integrin alpha-5/beta-1 is a receptor for fibrinogen. [1]
  • TGF-beta-mediated epithelial-mesenchymal transition of mammary epithelial cells is accompagnied by the loss of laminin-5 production and the upregulation of fibronectin and its alpha-5/beta-1 integrin receptor. [2]

Links to other resources

Binding hormones

  • fibrinogen
  • galectin-8
  • endostatin
  • fibronectin
  • NOV
    • Endothelial cells adhere to NOV protein via a mechanism that involves both αvβ3 and α5β1. [3]

Anatomical structures with this receptor

  • epithelial_cell