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Details for receptor: integrin alpha-5/beta-1

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EndoNet ID: ENR01105

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

It is also possible to use the search of EndoNet to link to the right detail page. The URL should look like 

http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
If the search pattern is unambigious the user is directed to the corresponding detail page.

Synonyms

  • integrin alpha-5/beta-1
  • integrin alpha5/beta1
  • integrin alpha5beta1
  • integrin alpha5-beta1

General information

  • Integrin alpha-5/beta-1 is a receptor for fibrinogen. [1]
  • TGF-beta-mediated epithelial-mesenchymal transition of mammary epithelial cells is accompagnied by the loss of laminin-5 production and the upregulation of fibronectin and its alpha-5/beta-1 integrin receptor. [2]

Links to other resources

Binding hormones

  • fibrinogen
  • galectin-8
  • endostatin
  • fibronectin
  • NOV
    • Endothelial cells adhere to NOV protein via a mechanism that involves both αvβ3 and α5β1. [3]

Anatomical structures with this receptor

  • epithelial_cell

Reference