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Details for receptor: VLA-4

EndoNet ID: ENR01106

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Synonyms

  • VLA-4
  • integrin alpha-4/beta-1
  • integrin alpha4/beta1

General information

Links to other resources

Subunit information

integrin beta-1 (1 times)

  • Isoform beta-1A is widely expressed, other isoforms are generally coexpressed with a more restricted distribution. [1]
Sequence
QTDENRCLK ANAKSCGEC IQAGPNCGW 
CTNSTFLQE GMPTSARCD DLEALKKKG 
CPPDDIENP RGSKDIKKN KNVTNRSKG 
TAEKLKPED IHQIQPQQL VLRLRSGEP 
QTFTLKFKR AEDYPIDLY YLMDLSYSM 
KDDLENVKS LGTDLMNEM RRITSDFRI 
GFGSFVEKT VMPYISTTP AKLRNPCTS 
EQNCTTPFS YKNVLSLTN KGEVFNELV 
GKQRISGNL DSPEGGFDA IMQVAVCGS 
LIGWRNVTR LLVFSTDAG FHFAGDGKL 
GGIVLPNDG QCHLENNMY TMSHYYDYP 
SIAHLVQKL SENNIQTIF AVTEEFQPV 
YKELKNLIP KSAVGTLSA NSSNVIQLI 
IDAYNSLSS EVILENGKL SEGVTISYK 
SYCKNGVNG TGENGRKCS NISIGDEVQ 
FEISITSNK CPKKDSDSF KIRPLGFTE 
EVEVILQYI CECECQSEG IPESPKCHE 
GNGTFECGA CRCNEGRVG RHCECSTDE 
VNSEDMDAY CRKENSSEI CSNNGECVC 
GQCVCRKRD NTNEIYSGK FCECDNFNC 
DRSNGLICG GNGVCKCRV CECNPNYTG 
SACDCSLDT STCEASNGQ ICNGRGICE 
CGVCKCTDP KFQGQTCEM CQTCLGVCA 
EHKECVQCR AFNKGEKKD TCTQECSYF 
NITKVESRD KLPQPVQPD PVSHCKEKD 
VDDCWFYFT YSVNGNNEV MVHVVENPE 
CPTGPDIIP IVAGVVAGI VLIGLALLL 
IWKLLMIIH DRREFAKFE KEKMNAKWD 
TGENPIYKS AVTTVVNPK YEGK
UniProt P05556

integrin alpha-4 (1 times)

Sequence
YNVDTESAL LYQGPHNTL FGYSVVLHS 
HGANRWLLV GAPTANWLA NASVINPGA 
IYRCRIGKN PGQTCEQLQ LGSPNGEPC 
GKTCLEERD NQWLGVTLS RQPGENGSI 
VTCGHRWKN IFYIKNENK LPTGGCYGV 
PPDLRTELS KRIAPCYQD YVKKFGENF 
ASCQAGISS FYTKDLIVM GAPGSSYWT 
GSLFVYNIT TNKYKAFLD KQNQVKFGS 
YLGYSVGAG HFRSQHTTE VVGGAPQHE 
QIGKAYIFS IDEKELNIL HEMKGKKLG 
SYFGASVCA VDLNADGFS DLLVGAPMQ 
STIREEGRV FVYINSGSG AVMNAMETN 
LVGSDKYAA RFGESIVNL GDIDNDGFE 
DVAIGAPQE DDLQGAIYI YNGRADGIS 
STFSQRIEG LQISKSLSM FGQSISGQI 
DADNNGYVD VAVGAFRSD SAVLLRTRP 
VVIVDASLS HPESVNRTK FDCVENGWP 
SVCIDLTLC FSYKGKEVP GYIVLFYNM 
SLDVNRKAE SPPRFYFSS NGTSDVITG 
SIQVSSREA NCRTHQAFM RKDVRDILT 
PIQIEAAYH LGPHVISKR STEEFPPLQ 
PILQQKKEK DIMKKTINF ARFCAHENC 
SADLQVSAK IGFLKPHEN KTYLAVGSM 
KTLMLNVSL FNAGDDAYE TTLHVKLPV 
GLYFIKILE LEEKQINCE VTDNSGVVQ 
LDCSIGYIY VDHLSRIDI SFLLDVSSL 
SRAEEDLSI TVHATCENE EEMDNLKHS 
RVTVAIPLK YEVKLTVHG FVNPTSFVY 
GSNDENEPE TCMVEKMNL TFHVINTGN 
SMAPNVSVE IMVPNSFSP QTDKLFNIL 
DVQTTTGEC HFENYQRVC ALEQQKSAM 
QTLKGIVRF LSKTDKRLL YCIKADPHC 
LNFLCNFGK MESGKEASV HIQLEGRPS 
ILEMDETSA LKFEIRATG FPEPNPRVI 
ELNKDENVA HVLLEGLHH QRPKRYFTI 
VIISSSLLL GLIVLLLIS YVMWKAGFF 
KRQYKSILQ EENRRDSWS YINSKSNDD
UniProt P13612

Binding hormones

  • fibronectin

Anatomical structures with this receptor

    Reference