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Details for receptor: Tim-3

EndoNet ID: ENR01129

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  • Tim-3
  • hepatitis A virus cellular receptor 2
  • HAVcr-2
  • T cell Ig and mucin domain-containing protein 3
  • TIMD-3
  • T cell membrane protein 3
  • HAVCR2
  • TIM3
  • TIMD3

General information

  • A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9. [1]
  • Tim-3 is a T helper type 1 (T(H)1)-specific cell surface molecule that seems to regulate T(H)1 responses and the induction of peripheral tolerance. [2]

Links to other resources

UniProt Q8TDQ0
Ensembl ENST00000307851

Binding hormones

  • galectin-9

Anatomical structures with this receptor