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Details for receptor: Tim-3

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EndoNet ID: ENR01129

To link to the content of EndoNet use the EndoNet ID that is given on the detail pages in the format ENX0000, where X is a place holder for the type of the component (e. g. R for receptor or C for anatomical structure).
As URL for the linking append this ID to the detail page for this type of component.
For an hormone that would be: 

http://endonet.bioinf.med.uni-goettingen.de/hormone/ENH00000

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http://endonet.bioinf.med.uni-goettingen.de/search/ENC00000
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Synonyms

  • Tim-3
  • hepatitis A virus cellular receptor 2
  • HAVcr-2
  • T cell Ig and mucin domain-containing protein 3
  • TIMD-3
  • T cell membrane protein 3
  • HAVCR2
  • TIM3
  • TIMD3

General information

  • A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9. [1]
  • Tim-3 is a T helper type 1 (T(H)1)-specific cell surface molecule that seems to regulate T(H)1 responses and the induction of peripheral tolerance. [2]

Links to other resources

UniProt Q8TDQ0
Ensembl ENST00000307851

Binding hormones

  • galectin-9

Anatomical structures with this receptor

    Reference