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Details for receptor: CEA

EndoNet ID: ENR01136

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Synonyms

  • CEA
  • CD66e
  • carcinoembryonic antigen
  • CEA-related cell adhesion molecule 5
  • CEACAM5
  • meconium antigen 100
  • CEAM5

General information

  • Endogenous receptor for galectin-1. [1]
  • The expression of carcinoembryonic antigen (CEACAM5) on intestinal epithelial cells is involved in the activation of populations of regulatory CD8(+) T cells. [2]
  • CEACAM5 functions as a chemoattractant and as an adhesion molecule, and has been reported to promote the metastatic potential in some experimental tumors. [3]

Links to other resources

UniProt P06731
Ensembl ENST00000446434

Subunit information

CEAM5

Sequence
KLTIESTPF NVAEGKEVL LLVHNLPQH 
LFGYSWYKG ERVDGNRQI IGYVIGTQQ 
ATPGPAYSG REIIYPNAS LLIQNIIQN 
DTGFYTLHV IKSDLVNEE ATGQFRVYP 
ELPKPSISS NNSKPVEDK DAVAFTCEP 
ETQDATYLW WVNNQSLPV SPRLQLSNG 
NRTLTLFNV TRNDTASYK CETQNPVSA 
RRSDSVILN VLYGPDAPT ISPLNTSYR 
SGENLNLSC HAASNPPAQ YSWFVNGTF 
QQSTQELFI PNITVNNSG SYTCQAHNS 
DTGLNRTTV TTITVYAEP PKPFITSNN 
SNPVEDEDA VALTCEPEI QNTTYLWWV 
NNQSLPVSP RLQLSNDNR TLTLLSVTR 
NDVGPYECG IQNELSVDH SDPVILNVL 
YGPDDPTIS PSYTYYRPG VNLSLSCHA 
ASNPPAQYS WLIDGNIQQ HTQELFISN 
ITEKNSGLY TCQANNSAS GHSRTTVKT 
ITVSAELPK PSISSNNSK PVEDKDAVA 
FTCEPEAQN TTYLWWVNG QSLPVSPRL 
QLSNGNRTL TLFNVTRND ARAYVCGIQ 
NSVSANRSD PVTLDVLYG PDTPIISPP 
DSSYLSGAN LNLSCHSAS NPSPQYSWR 
INGIPQQHT QVLFIAKIT PNNNGTYAC 
FVSNLATGR NNSIVKSIT VSASGTSPG 
LSA
UniProt P06731

Binding hormones

  • galectin-1

Anatomical structures with this receptor

    Reference