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Details for receptor: complement receptor 3

EndoNet ID: ENR01144

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  • complement receptor 3
  • CR3
  • complement component 3a receptor 1
  • C3aR
  • C3a anaphylatoxin chemotactic receptor
  • C3a-R
  • C3R1

General information

  • G protein-coupled receptor that mediates various aspects of inflammatory and immune responses, including complement activation, chemotaxis, and actin stress fiber formation. [1]
  • Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. [2]

Links to other resources

UniProt Q16581
Ensembl ENST00000307637

Binding hormones

  • galectin-1

Anatomical structures with this receptor

  • astrocyte

  • bronchial_epithelial_cell

  • lung

  • central_nerve_system_element

  • neuron

  • glial_cell_of_central_nervous_system