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Details for receptor: CD74

EndoNet ID: ENR01163

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  • CD74
  • Ia-GAMMA
  • gamma chain of class II antigens
  • Class II associated invariant chain peptides
  • HLA-DR-gamma
  • Ia-associated invariant gamma
  • major histocompatibility complex II-associated gamma
  • HLA class II histocompatibility antigen gamma chain
  • Ii
  • p33

General information

  • MIF binds to the extracellular domain of CD74, and CD74 is required for MIF-induced activation of the extracellular signal-regulated kinase-1/2 MAP kinase cascade, cell proliferation, and PGE2 production. [1]

Links to other resources

UniProt P04233
Ensembl ENST00000377795

Binding hormones

  • MIF

Anatomical structures with this receptor