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Details for receptor: syndecan

EndoNet ID: ENR01166

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  • syndecan

General information

  • Heparin/HS is an integral component of the minimal Slit-Robo signaling complex and serves to stabilize the relatively weak Slit-Robo interaction. [1]
  • Both Slit and Robo can be co-immunoprecipitated with syndecan. [1]
  • Syndecan is a membrane-spanning protein to which are covalently attached several HS chains, consisting of repeating sulfated disaccharide units. [1]
  • Cell surface heparan sulfate/chondroitin sulfate proteoglycan, can act as a coreceptor for integrin ligation and create a synergistic signaling response.

Links to other resources

Binding hormones

  • slit-2 isoform 1 N-product
  • laminin-1
  • slit-3 isoform 1
  • slit-1
  • slit-2 isoform 1 C-product

Anatomical structures with this receptor