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Details for receptor: IL-18R

EndoNet ID: ENR01176

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Synonyms

  • IL-18R
  • interleukin 18 receptor
  • IL18R1:IL18RAP

General information

Links to other resources

UniProt O95256
Ensembl ENST00000450855

Subunit information

interleukin-18 receptor 1

Sequence
AESCTSRPH ITVVEGEPF YLKHCSCSL 
AHEIETTTK SWYKSSGSQ EHVELNPRS 
SSRIALHDC VLEFWPVEL NDTGSYFFQ 
MKNYTQKWK LNVIRRNKH SCFTERQVT 
SKIVEVKKF FQITCENSY YQTLVNSTS 
LYKNCKKLL LENNKNPTI KKNAEFEDQ 
GYYSCVHFL HHNGKLFNI TKTFNITIV 
EDRSNIVPV LLGPKLNHV AVELGKNVR 
LNCSALLNE EDVIYWMFG EENGSDPNI 
HEEKEMRIM TPEGKWHAS KVLRIENIG 
ESNLNVLYN CTVASTGGT DTKSFILVR 
KADMADIPG HVFTRGMII AVLILVAVV 
CLVTVCVIY RVDLVLFYR HLTRRDETL 
TDGKTYDAF VSYLKECRP ENGEEHTFA 
VEILPRVLE KHFGYKLCI FERDVVPGG 
AVVDEIHSL IEKSRRLII VLSKSYMSN 
EVRYELESG LHEALVERK IKIILIEFT 
PVTDFTFLP QSLKLLKSH RVLKWKADK 
SLSYNSRFW KNLLYLMPA KTVKPGRDE 
PEVLPVLSE S
UniProt Q13478

interleukin-18 receptor accessory protein

Sequence
FNISGCSTK KLLWTYSTR SEEEFVLFC 
DLPEPQKSH FCHRNRLSP KQVPEHLPF 
MGSNDLSDV QWYQQPSNG DPLEDIRKS 
YPHIIQDKC TLHFLTPGV NNSGSYICR 
PKMIKSPYD VACCVKMIL EVKPQTNAS 
CEYSASHKQ DLLLGSTGS ISCPSLSCQ 
SDAQSPAVT WYKNGKLLS VERSNRIVV 
DEVYDYHQG TYVCDYTQS DTVSSWTVR 
AVVQVRTIV GDTKLKPDI LDPVEDTLE 
VELGKPLTI SCKARFGFE RVFNPVIKW 
YIKDSDLEW EVSVPEAKS IKSTLKDEI 
IERNIILEK VTQRDLRRK FVCFVQNSI 
GNTTQSVQL KEKRGVVLL YILLGTIGT 
LVAVLAASA LLYRHWIEI VLLYRTYQS 
KDQTLGDKK DFDAFVSYA KWSSFPSEA 
TSSLSEEHL ALSLFPDVL ENKYGYSLC 
LLERDVAPG GVYAEDIVS IIKRSRRGI 
FILSPNYVN GPSIFELQA AVNLALDDQ 
TLKLILIKF CYFQEPESL PHLVKKALR 
VLPTVTWRG LKSVPPNSR FWAKMRYHM 
PVKNSQGFT WNQLRITSR IFQWKGLSR 
TETTGRSSQ PKEW
UniProt O95256

Binding hormones

  • IL-18

Anatomical structures with this receptor

  • T-lymphocyte

    Influences

    • positive IFN-gamma
  • helper_T_cell_Th1

    Influences

    • positive IFN-gamma
      • IL-18 is originally called interferon gamma inducing factor, due to its capacity to induce interferon gamma production in Th1 type cells. [1]
Reference