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Details for receptor: EAAT4

EndoNet ID: ENR01224

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Synonyms

  • EAAT4
  • excitatory amino acid transporter 4
  • SLC1A6
  • solute carrier family 1 member 6
  • sodium-dependent glutamate/aspartate transporter

General information

  • Expressed densely and selectively in cell bodies of Purkinje cells. [1]

Links to other resources

UniProt P48664
Ensembl ENST00000430939

Subunit information

Sequence
MSSHGNSLF LRESGQRLG RVGWLQRLQ 
ESLQQRALR TRLRLQTMT LEHVLRFLR 
RNAFILLTV SAVVIGVSL AFALRPYQL 
TYRQIKYFS FPGELLMRM LQMLVLPLI 
VSSLVTGMA SLDNKATGR MGMRAAVYY 
MVTTIIAVF IGILMVTII HPGKGSKEG 
LHREGRIET IPTADAFMD LIRNMFPPN 
LVEACFKQF KTQYSTRVV TRTMVRTEN 
GSEPGASMP PPFSVENGT SFLENVTRA 
LGTLQEMLS FEETVPVPG SANGINALG 
LVVFSVAFG LVIGGMKHK GRVLRDFFD 
SLNEAIMRL VGIIIWYAP VGILFLIAG 
KILEMEDMA VLGGQLGMY TLTVIVGLF 
LHAGIVLPL IYFLVTHRN PFPFIGGML 
QALITAMGT SSSSATLPI TFRCLEEGL 
GVDRRITRF VLPVGATVN MDGTALYEA 
LAAIFIAQV NNYELNLGQ ITTISITAT 
AASVGAAGI PQAGLVTMV IVLTSVGLP 
TEDITLIIA VDWFLDRLR TMTNVLGDS 
IGAAVIEHL SQRELELQE AELTLPSLG 
KPYKSLMAQ EKGASRGRG GNESAM

Binding hormones

  • D-aspartate
  • L-aspartate
  • L-glutamate

Anatomical structures with this receptor

  • Purkinje_cell

    Induced phenotypes

    • glutamate transport
      • EAAT4 controls the transport of glutamate by different anion fluxes. [2]
Reference