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Details for receptor: Gamma-aminobutyric acid receptor A

EndoNet ID: ENR01299

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Synonyms

  • Gamma-aminobutyric acid receptor A

General information

  • GABAA receptors are pentameric membrane proteins that operate as GABA-gated Clorid channels [1]
  • the most common GABA receptor in the mammalian CNS consists of two copies each of the alpha 1 and beta 2 subunits together with a single gamma 2 subunit. [2]

Links to other resources

Subunit information

Gamma-aminobutyric acid receptor subunit alpha-1

Sequence
QPSLQDELK DNTTVFTRI LDRLLDGYD 
NRLRPGLGE RVTEVKTDI FVTSFGPVS 
DHDMEYTID VFFRQSWKD ERLKFKGPM 
TVLRLNNLM ASKIWTPDT FFHNGKKSV 
AHNMTMPNK LLRITEDGT LLYTMRLTV 
RAECPMHLE DFPMDAHAC PLKFGSYAY 
TRAEVVYEW TREPARSVV VAEDGSRLN 
QYDLLGQTV DSGIVQSST GEYVVMTTH 
FHLKRKIGY FVIQTYLPC IMTVILSQV 
SFWLNRESV PARTVFGVT TVLTMTTLS 
ISARNSLPK VAYATAMDW FIAVCYAFV 
FSALIEFAT VNYFTKRGY AWDGKSVVP 
EKPKKVKDP LIKKNNTYA PTATSYTPN 
LARGDPGLA TIAKSATIE PKEVKPETK 
PPEPKKTFN SVSKIDRLS RIAFPLLFG 
IFNLVYWAT YLNREPQLK APTPHQ
UniProt P14867

butyric acid receptor subunit gamma-2

Sequence
QKSDDDYED YASNKTWVL TPKVPEGDV 
TVILNNLLE GYDNKLRPD IGVKPTLIH 
TDMYVNSIG PVNAINMEY TIDIFFAQT 
WYDRRLKFN STIKVLRLN SNMVGKIWI 
PDTFFRNSK KADAHWITT PNRMLRIWN 
DGRVLYTLR LTIDAECQL QLHNFPMDE 
HSCPLEFSS YGYPREEIV YQWKRSSVE 
VGDTRSWRL YQFSFVGLR NTTEVVKTT 
SGDYVVMSV YFDLSRRMG YFTIQTYIP 
CTLIVVLSW VSFWINKDA VPARTSLGI 
TTVLTMTTL STIARKSLP KVSYVTAMD 
LFVSVCFIF VFSALVEYG TLHYFVSNR 
KPSKDKDKK KKNPAPTID IRPRSATIQ 
MNNATHLQE RDEEYGYEC LDGKDCASF 
FCCFEDCRT GAWRHGRIH IRIAKMDSY 
ARIFFPTAF CLFNLVYWV SYLYL
UniProt P18507

butyric acid receptor subunit beta-2

Binding hormones

  • GABA

Anatomical structures with this receptor

  • central_nerve_system_element

Reference