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Details for receptor: Sterol O-acyltransferase 1

EndoNet ID: ENR01310

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Synonyms

  • Acyl coenzyme A:cholesterol acyltransferase 1
  • ACAT-1
  • Sterol O-acyltransferase 1
  • Cholesterol acyltransferase 1

General information

  • Catalyzes the formation of fatty acid-cholesterol esters. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.

Links to other resources

UniProt P35610
Ensembl ENST00000367619

Binding hormones

    Anatomical structures with this receptor

    • hepatocyte

      Influences

      • positive apo B-100
        • Cholesteryl esters play an important role in regulating the assembly and secretion of apoB-containing lipoproteins. [1]
      • positive apo B-48
        • Cholesteryl esters play an important role in regulating the assembly and secretion of apoB-containing lipoproteins. [1]
    Reference