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Details for receptor: ATP-binding cassette sub-family A member 1

EndoNet ID: ENR01311

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Synonyms

  • ATP-binding cassette sub-family A member 1
  • ATP-binding cassette transporter 1
  • Cholesterol efflux regulatory protein
  • ABCA1

General information

Links to other resources

UniProt O95477
Ensembl ENST00000374736

Binding hormones

    Anatomical structures with this receptor

    • macrophage

      Influences

      • positive cholesterol
        • It is likely that ABCA1 is the cAMP-inducible apolipoprotein receptor that promotes secretion of lipids from macrophages. [1]
        • There was an investigation whether ABCA1 expression is also responsible for the apoA-I-mediated cholesterol efflux induced by cAMP in macrophages and whether this involves direct binding of apoA-I to plasma membrane ABCA1. [1]
    Reference