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Details for receptor: GPR39 protein

EndoNet ID: ENR01312

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  • GPR39 protein
  • GPR39

General information

  • Belongs to the G-protein coupled receptor 1 family.
  • GPR39 is a novel inhibitor of cell death, which might represent a therapeutic target with implications for processes involving apoptosis and endoplasmic reticulum stress like cancer, ischemia/reperfusion injury, and neurodegenerative disease. [1]

Links to other resources

UniProt A4FVA5
Ensembl ENST00000329321

Binding hormones

    Anatomical structures with this receptor

    • hippocampus


      • positive pigment epithelium-derived factor
        • GPR39 overexpression leads to increased secretion of the cytoprotective pigment epithelium-dereived growth factor (PEDF). [1]