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Details for receptor: Lysophosphatidic acid receptor 4

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EndoNet ID: ENR01321

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Synonyms

  • P2Y purinoceptor 9
  • P2Y5-like receptor
  • Purinergic receptor 9
  • G-protein coupled receptor 23
  • LPAR4
  • Lysophosphatidic acid receptor 4
  • LPA receptor 4

General information

  • Belongs to the G-protein coupled receptor 1 family.

Links to other resources

UniProt Q99677
Ensembl ENST00000373301

Subunit information

Subunit (1 times)

Sequence 
MGDRRFIDF QFQDSNSSL RPRLGNATA 
NNTCIVDDS FKYNLNGAV YSVVFILGL 
ITNSVSLFV FCFRMKMRS ETAIFITNL 
AVSDLLFVC TLPFKIFYN FNRHWPFGD 
TLCKISGTA FLTNIYGSM LFLTCISVD 
RFLAIVYPF RSRTIRTRR NSAIVCAGV 
WILVLSGGI SASLFSTTN VNNATTTCF 
EGFSKRVWK TYLSKITIF IEVVGFIIP 
LILNVSCSS VVLRTLRKP ATLSQIGTN 
KKKVLKMIT VHMAVFVVC FVPYNSVLF 
LYALVRSQA ITNCFLERF AKIMYPITL 
CLATLNCCF DPFIYYFTL ESFQKSFYI 
NAHIRMESL FKTETPLTT KPSLPAIQE 
EVSDQTTNN GGELMLEST F
UniProt Q99677-1

Binding hormones

  • lysophosphatidic acid
    • Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Transduces a signal by increasing the intracellular calcium ions and by stimulating adenylyl cyclase activity. The rank order of potency for agonists of this receptor is 1-oleoyl- > 1-stearoyl- > 1-palmitoyl- > 1-myristoyl- > 1-alkyl- > 1-alkenyl-LPA. [1]

Anatomical structures with this receptor

  • ovary

  • brain

  • heart

  • small_intestine

  • testis

  • prostate

  • colon

  • spleen

  • thymus

  • pancreas

  • kidney

  • skeleton_muscle

Reference