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Details for receptor: Syndecan-3

EndoNet ID: ENR01341

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Synonyms

  • Syndecan-3
  • SDC3

General information

  • Syndecan-3 belongs to the syndecan family and is a transmembrane protein. [1]
  • Its extracellular domain contains 3 glycosaminoglycan attachment sites. [1]

Links to other resources

UniProt O75056
Ensembl ENST00000339394

Subunit information

Sequence
MKPGPPHRA GAAHGAGAG AGAAAGPGA 
RGLLLPPLL LLLLAGRAA GAQRWRSEN 
FERPVDLEG SGDDDSFPD DELDDLYSG 
SGSGYFEQE SGIETAMRF SPDVALAVS 
TTPAVLPTT NIQPVGTPF EELPSERPT 
LEPATSPLV VTEVPEEPS QRATTVSTT 
MATTAATST GDPTVATVP ATVATATPS 
TPAAPPFTA TTAVIRTTG VRRLLPLPL 
TTVATARAT TPEAPSPPT TAAVLDTEA 
PTPRLVSTA TSRPRALPR PATTQEPDI 
PERSTLPLG TTAPGPTEV AQTPTPETF 
LTTIRDEPE VPVSGGPSG DFELPEEET 
TQPDTANEV VAVGGAAAK ASSPPGTLP 
KGARPGPGL LDNAIDSGS SAAQLPQKS 
ILERKEVLV AVIVGGVVG ALFAAFLVT 
LLIYRMKKK DEGSYTLEE PKQASVTYQ 
KPDKQEEFY A

Binding hormones

  • PTN
    • PTN signals through three cell surface receptors: one of them is syndecan-3. [1]

Anatomical structures with this receptor

  • neuron

    Induced phenotypes

    • neurite elongation
      • The binding of PTN with syndecan-3 induces neurite outgrowth of embryonic neurons. [1]
    • Syndecan-3 mRNA is mostly expressed in the nervous system, on neuronal cells. [2]
Reference