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Details for receptor: Secretin receptor

EndoNet ID: ENR01350

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Synonyms

  • Secretin receptor
  • SCT-R
  • SCTR

General information

  • The secretin receptor (SCTR) is a member of Class II B1 guanine nucleotide binding protein (G protein)-coupled receptors (GPCR). [1]
  • This class of GPCR utilizes intracellular second messengers including cyclic AMP and calcium ions in signaling pathways. [1]

Links to other resources

UniProt P47872

Subunit information

secretin receptor

Sequence
MRPHLSPPL QQLLLPVLL ACAAHSTGA 
LPRLCDVLQ VLWEEQDQC LQELSREQT 
GDLGTEQPV PGCEGMWDN ISCWPSSVP 
GRMVEVECP RFLRMLTSR NGSLFRNCT 
QDGWSETFP RPNLACGVN VNDSSNEKR 
HSYLLKLKV MYTVGYSSS LVMLLVALG 
ILCAFRRLH CTRNYIHMH LFVSFILRA 
LSNFIKDAV LFSSDDVTY CDAHRAGCK 
LVMVLFQYC IMANYSWLL VEGLYLHTL 
LAISFFSER KYLQGFVAF GWGSPAIFV 
ALWAIARHF LEDVGCWDI NANASIWWI 
IRGPVILSI LINFILFIN ILRILMRKL 
RTQETRGNE VSHYKRLAR STLLLIPLF 
GIHYIVFAF SPEDAMEIQ LFFELALGS 
FQGLVVAVL YCFLNGEVQ LEVQKKWQQ 
WHLREFPLH PVASFSNST KASHLEQSQ 
GTCRTSII

Binding hormones

  • secretin
    • Secretin carries out its hormonal actions through the secretin receptor (SCTR). [1]

Anatomical structures with this receptor

  • cerebellum

    • The existence of secretin and secretin receptor in the cerebellum was confirmed by others using an immunohistochemical and an in vitro autoradiographic approach. [2]
Reference